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1

Development of Thiophenic Analogues of Benzothiadiazine Dioxides as New Powerful Potentiators of 2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid (AMPA) Receptors

Francotte, Pierre, Goffin, Eric, Fraikin, Pierre, Graindorge, E., Lestage, Pierre, Danober, Laurence, Challal, Sylvie, Rogez, Nathalie, Nosjean, Olivier, Caignard, Daniel-Henri, Pirotte, Bernard, de T

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.03 MB

english, 2013

2

Detergent-free Isolation of Functional G Protein-Coupled Receptors into Nanometric Lipid Particles

Logez, Christel, Damian, Marjorie, Legros, Céline, Dupré, Clémence, Guéry, Mélody, Mary, Sophie, Wagner, Renaud, M’Kadmi, Céline, Nosjean, Olivier, Fould, Benjamin, Marie, Jacky, Fehrentz, Jean-Alain,

Journal:

Year:

2015

Language:

english

File:

PDF, 1.57 MB

english, 2015

3

Glossary of terms used in biomolecular screening (IUPAC Recommendations 2011)

Proudfoot, John, Nosjean, Olivier, Blanchard, Jan, Wang, John, Besson, Dominique, Crankshaw, Denis, Gauglitz, Günter, Hertzberg, Robert, Homon, Carol, Llewellyn, Lyndon, Neubig, Richard, Walker, Larry

Journal:

Pure & Applied Chemistry

Year:

2011

Language:

english

File:

PDF, 321 KB

english, 2011

4

Screening of protein kinase inhibitors identifies PKC inhibitors as inhibitors of osteoclastic acid secretion and bone resorption

Mette G Sørensen, Morten A Karsdal, Morten H Dziegiel, Jean A Boutin, Olivier Nosjean, Kim Henriksen

Journal:

BMC Musculoskeletal Disorders

Year:

2010

Language:

english

File:

PDF, 1.22 MB

english, 2010

5

Identification of catalytic and nonâcatalytic activity inhibitors against PRC2âEZH2 complex through multiple highâthroughput screening campaigns

Zhou, Yan, Du, Daoâhai, Wang, Jia, Cai, Xiaoâqing, Deng, Alicia X., Nosjean, Olivier, Boutin, Jean A., Renard, Pierre, Yang, Deâhua, Luo, Cheng, Wang, MingâWei

Journal:

Chemical Biology & Drug Design

Year:

2020

File:

PDF, 28.60 MB

2020

6

Design and synthesis of 1-(2-alkanamidoethyl)-6-methoxy-7-azaindole derivatives as potent melatonin agonists

Matthieu Jeanty, Franck Suzenet, Philippe Delagrange, Olivier Nosjean, Jean A. Boutin, Daniel H. Caignard, Gérald Guillaumet

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 627 KB

english, 2011

7

New melatonin (MT1/MT2) ligands: Design and synthesis of (8,9-dihydro-7H-furo[3,2-f]chromen-1-yl) derivatives

Landagaray, Elodie, Ettaoussi, Mohamed, Leclerc, Véronique, Traoré, Balla, Perez, Valérie, Nosjean, Olivier, Boutin, Jean A., Caignard, Daniel-Henri, Delagrange, Philippe, Berthelot, Pascal, Yous, Saï

Journal:

Bioorganic & Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 616 KB

english, 2014

8

Ectoplasmic insertion of a glycosylphosphatidylinositol-anchored protein in glycosphingolipid- and cholesterol-containing phosphatidylcholine vesicles

Olivier Nosjean, Bernard Roux

Journal:

Year:

1999

Language:

english

File:

PDF, 519 KB

english, 1999

9

Synthesis, chiral resolution, absolute configuration assignment and pharmacological evaluation of a series of melatoninergic ligands

Ettaoussi, Mohamed, Pérès, Basile, Jarry, Christian, Nosjean, Olivier, Boutin, Jean A., Gohier, Arnaud, Mannoury la Cour, Clotilde, Caignard, Daniel-Henri, Delagrange, Philippe, Berthelot, Pascal, You

Journal:

Year:

2014

Language:

english

File:

PDF, 379 KB

english, 2014

10

New substrate analogues of human serotonin N-acetyltransferase produce in situ specific and potent inhibitors

Gilles Ferry, Caroline Ubeaud, Julien Mozo, Christophe Péan, Philippe Hennig, Marianne Rodriguez, Catherine Scoul, Anne Bonnaud, Olivier Nosjean, Jean-Pierre Galizzi, Philippe Delagrange, Pierre Renar

Journal:

Year:

2004

Language:

english

File:

PDF, 497 KB

english, 2004

11

B Cell Survival in Intragraft Tertiary Lymphoid Organs After Rituximab Therapy

Thaunat, Olivier, Patey, Natacha, Gautreau, Chantal, Lechaton, Sophie, Fremeaux-Bacchi, Véronique, Dieu-Nosjean, Marie-Caroline, Cassuto-Viguier, Elisabeth, Legendre, Christophe, Delahousse, Michel, L

Journal:

Transplantation Journal

Year:

2008

Language:

english

File:

PDF, 1.63 MB

english, 2008

12

Screening ubiquitin specific protease activities using chemically synthesized ubiquitin and ubiquitinated peptides

Bacchi, Marine, Fould, Benjamin, Jullian, Magali, Kreiter, Aude, Maurras, Amélie, Nosjean, Olivier, Coursindel, Thibault, Puget, Karine, Ferry, Gilles, Boutin, Jean A.

Journal:

Analytical Biochemistry

Year:

2017

Language:

english

File:

PDF, 6.20 MB

english, 2017

13

Correction: Synthesis, chiral resolution, absolute configuration assignment and pharmacological evaluation of a series of melatoninergic ligands

Ettaoussi, Mohamed, Pérès, Basile, Jarry, Christian, Pallage, Viviane, Nosjean, Olivier, Boutin, Jean A., Gohier, Arnaud, Mannoury la Cour, Clotilde, Caignard, Daniel-Henri, Delagrange, Philippe, Bert

Journal:

Year:

2014

Language:

english

File:

PDF, 150 KB

english, 2014

14

Thermal and pH stabilities of alkaline phosphatase from bovine intestinal mucosa: a FTIR study

Laurence de La Fournière, Olivier Nosjean, René Buchet, Bernard Roux

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1995

Language:

english

File:

PDF, 603 KB

english, 1995

15

High-Throughput Screening for GPR119 Modulators Identifies a Novel Compound with Anti-Diabetic Efficacy in db/db Mice

Zhang, Meng, Feng, Yang, Wang, Jia, Zhao, Jianwei, Li, Ting, He, Min, Yang, Dehua, Nosjean, Olivier, Boutin, Jean, Renard, Pierre, Wang, Ming-Wei, Xu, Aimin

Journal:

Year:

2013

Language:

english

File:

PDF, 2.58 MB

english, 2013

16

Description of the constitutive activity of cloned human melatonin receptors hMT1 and hMT2 and discovery of inverse agonists

Séverine Devavry, Céline Legros, Chantal Brasseur, Philippe Delagrange, Gilberto Spadoni, William Cohen, Benoît Malpaux, Jean A. Boutin, Olivier Nosjean

Journal:

Journal of Pineal Research

Year:

2012

Language:

english

File:

PDF, 899 KB

english, 2012

17

Mammalian GPI proteins: sorting, membrane residence and functions

Olivier Nosjean, Anne Briolay, Bernard Roux

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes

Year:

1997

Language:

english

File:

PDF, 398 KB

english, 1997

18

Ion Transporters Involved in Acidification of the Resorption Lacuna in Osteoclasts

Kim Henriksen, Mette G. Sørensen, Vicki K. Jensen, Morten H. Dziegiel, Olivier Nosjean, Morten A. Karsdal

Journal:

Calcified Tissue International

Year:

2008

Language:

english

File:

PDF, 830 KB

english, 2008

19

[Methods in Enzymology] Liposomes, Part B Volume 372 || Anchoring of Glycosylphosphatidylinositol–Proteins to Liposomes

Nosjean, Olivier

Year:

2003

Language:

english

File:

PDF, 204 KB

english, 2003

20

Biologically active tetralones from New Caledonian Zygogynum spp.

Noureddine Allouche, Barbara Morleo, Odile Thoison, Vincent Dumontet, Olivier Nosjean, Françoise Guéritte, Thierry Sévenet, Marc Litaudon

Journal:

Year:

2008

Language:

english

File:

PDF, 166 KB

english, 2008

21

Image-free assessment of protein translocation in live cells

Christophe Furger, Sylvain Derick, Jean A Boutin, Olivier Nosjean

Journal:

Current Opinion in Pharmacology

Year:

2009

Language:

english

File:

PDF, 425 KB

english, 2009

22

S38151 [p-guanidinobenzoyl-[Des-Gly10]-MCH(7-17)] is a potent and selective antagonist at the MCH1 receptor and has anti-feeding properties in vivo

Valérie Audinot, Odile Della Zuana, Nelly Fabry, Christine Ouvry, Olivier Nosjean, Jean-Michel Henlin, Jean-Luc Fauchère, Jean A. Boutin

Journal:

Year:

2009

Language:

english

File:

PDF, 862 KB

english, 2009

23

Recombinant Human Melatonin Receptor MT1 Isolated in Mixed Detergents Shows Pharmacology Similar to That in Mammalian Cell Membranes

Logez, Christel, Berger, Sylvie, Legros, Céline, Banères, Jean-Louis, Cohen, William, Delagrange, Philippe, Nosjean, Olivier, Boutin, Jean A., Ferry, Gilles, Simonin, Frédéric, Wagner, Renaud, Tosini,

Journal:

Year:

2014

Language:

english

File:

PDF, 1.19 MB

english, 2014

24

Synthesis and Pharmacological Evaluation of a series of the Agomelatine Analogues as Melatonin MT 1 /MT 2 Agonist and 5-HT 2C Antagonist

Ettaoussi, Mohamed, Sabaouni, Ahmed, Pérès, Basile, Landagaray, Elodie, Nosjean, Olivier, Boutin, Jean A., Caignard, Daniel-Henri, Delagrange, Philippe, Berthelot, Pascal, Yous, Saïd

Journal:

Year:

2013

Language:

english

File:

PDF, 566 KB

english, 2013

25

New MT2 Melatonin Receptor-Selective Ligands: Agonists and Partial Agonists

Boutin, Jean, Bonnaud, Anne, Brasseur, Chantal, Bruno, Olivier, Lepretre, Nolwenn, Oosting, Peter, Coumailleau, Sophie, Delagrange, Philippe, Nosjean, Olivier, Legros, Céline

Journal:

International Journal of Molecular Sciences

Year:

2017

Language:

english

File:

PDF, 2.25 MB

english, 2017

26

A Quantitative Assay for Lysosomal Acidification Rates in Human Osteoclasts

Jensen, Vicki Kaiser, Nosjean, Olivier, Dziegiel, Morten Hanefeld, Boutin, Jean A., Sørensen, Mette Grøndahl, Karsdal, Morten Asser, Henriksen, Kim

Journal:

Assay and Drug Development Technologies

Year:

2011

Language:

english

File:

PDF, 808 KB

english, 2011

27

W2476 ameliorates β-cell dysfunction and exerts therapeutic effects in mouse models of diabetes via modulation of the thioredoxin-interacting protein signaling pathway

Li, Ting, Lin, Guang-yao, Zhong, Li, Zhou, Yan, Wang, Jia, Zhu, Yue, Feng, Yang, Cai, Xiao-qing, Liu, Qing, Nosjean, Olivier, Boutin, Jean A, Renard, Pierre, Yang, De-hua, Wang, Ming-wei

Journal:

Acta Pharmacologica Sinica

Year:

2017

Language:

english

File:

PDF, 11.83 MB

english, 2017

28

Cytotoxic Pentacyclic Triterpenoids from Combretum sundaicum and Lantana camara as Inhibitors of Bcl-xL/BakBH3 Domain Peptide Interaction

Litaudon, Marc, Jolly, Claire, Le Callonec, Catherine, Cuong, Dao Din, Retailleau, Pascal, Nosjean, Olivier, Nguyen, Van Hung, Pfeiffer, Bruno, Boutin, Jean A., Guéritte, Françoise

Journal:

Journal of Natural Products

Year:

2009

Language:

english

File:

PDF, 775 KB

english, 2009

29

A Dimeric Sesquiterpenoid from a Malaysian Meiogyne as a New Inhibitor of Bcl-xL/BakBH3 Domain Peptide Interaction ⊥

Litaudon, Marc, Bousserouel, Hadjira, Awang, Khalijah, Nosjean, Olivier, Martin, Marie-Thérèse, Dau, Marie Elise Tran Huu, Hadi, Hamid A, Boutin, Jean A., Sévenet, Thierry, Guéritte, Françoise

Journal:

Journal of Natural Products

Year:

2009

Language:

english

File:

PDF, 323 KB

english, 2009

30

Selective sequestration of X4 isolates by human genital epithelial cells: Implication for virus tropism selection process during sexual transmission of HIV

Willy Berlier, Thomas Bourlet, Philip Lawrence, Hind Hamzeh, Claude Lambert, Christian Genin, Bernard Verrier, Marie-Caroline Dieu-Nosjean, Bruno Pozzetto, Olivier Delézay

Journal:

Journal of Medical Virology

Year:

2005

Language:

english

File:

PDF, 484 KB

english, 2005

31

No prokaryotic GPI anchoring

Nosjean, Olivier

Journal:

Nature Biotechnology

Year:

1998

File:

PDF, 248 KB

1998

32

Characterization of the Mel1c melatoninergic receptor in platypus (Ornithorhynchus anatinus)

Gautier, Célia, Guenin, Sophie-Penelope, Riest-Fery, Isabelle, Perry, Tahlia Jade, Legros, Céline, Nosjean, Olivier, Simonneaux, Valerie, Grützner, Frank, Boutin, Jean A., Janke, Axel

Journal:

Year:

2018

Language:

english

File:

PDF, 17.88 MB

english, 2018

33

Melatonin MT 1 and MT 2 receptors display different molecular pharmacologies only in the G-protein coupled state

Legros, Céline, Devavry, Séverine, Caignard, Sarah, Tessier, Clémence, Delagrange, Philippe, Ouvry, Christine, Boutin, Jean A, Nosjean, Olivier

Journal:

British Journal of Pharmacology

Year:

2014

Language:

english

File:

PDF, 2.91 MB

english, 2014

34

Coexpression of major histocompatibility complex class II with chemokines and nuclear NFκB p50 in melanoma: a rational for their association with poor prognosis

Martins, Isabelle, Sylla, Khaoussou, Deshayes, Frederique, Lauriol, Jessica, Ghislin, Stephanie, Dieu-Nosjean, Marie-Caroline, Viguier, Manuelle, Verola, Olivier, Charron, Dominique, Alcaide-Loridan,

Journal:

Melanoma Research

Year:

2009

Language:

english

File:

PDF, 556 KB

english, 2009

35

Human tissue non-specific alkaline phosphatases: sugar-moiety-induced enzymic and antigenic modulations and genetic aspects

NOSJEAN, Olivier, KOYAMA, Iwao, GOSEKI, Masae, ROUX, Bernard, KOMODA, Tsugikazu

Journal:

Biochemical Journal

Year:

1997

Language:

english

File:

PDF, 490 KB

english, 1997

36

Editorial overview: New technologies: multidisciplinary evolutions for drug discovery

Bril, Antoine, Nosjean, Olivier

Journal:

Current Opinion in Pharmacology

Year:

2018

Language:

english

File:

PDF, 229 KB

english, 2018

37

Molecular and cellular pharmacological properties of 5-methoxycarbonylamino-N-acetyltryptamine (MCA-NAT): a nonspecific MT3 ligand

Ludwig Vincent, William Cohen, Philippe Delagrange, Jean A. Boutin, Olivier Nosjean

Journal:

Journal of Pineal Research

Year:

2010

Language:

english

File:

PDF, 396 KB

english, 2010

38

Mechanistic characterization of S 38093, a novel inverse agonist at histamine H3 receptors

Sors, Aurore, Panayi, Fany, Bert, Lionel, Favale, Dominique, Nosjean, Olivier, Audinot, Valérie, Arrang, Jean-Michel, Buisson, Bruno, Steidl, Esther, Delbos, Jean-Marie, Huhtala, Tuulia, Kontkanen, Ou

Journal:

European Journal of Pharmacology

Year:

2017

Language:

english

File:

PDF, 1.20 MB

english, 2017

39

A Variant Alkaline Phosphatase Detected in a Patient with Lung Cancer

Komoda, Tsugikazu, Nosjean, Olivier, Honma, Keiichi, Nemoto, Keiichi, Sato, Toyoji, Miyanaga, Mieko, Sugimoto, Hideo

Journal:

Enzyme and Protein

Year:

1996

File:

PDF, 618 KB

1996

40

Natural ligands of PPARγ:: Are prostaglandin J2 derivatives really playing the part?

Olivier Nosjean, Jean A Boutin

Journal:

Cellular Signalling

Year:

2002

Language:

english

File:

PDF, 262 KB

english, 2002

41

Total chemical synthesis, refolding, and crystallographic structure of fully active immunophilin calstabin 2 (FKBP12.6)

Bacchi, Marine, Jullian, Magali, Sirigu, Serena, Fould, Benjamin, Huet, Tiphaine, Bruyand, Lisa, Antoine, Mathias, Vuillard, Laurent, Ronga, Luisa, Chavas, Leonard M.G., Nosjean, Olivier, Ferry, Gille

Journal:

Protein Science

Year:

2016

Language:

english

File:

PDF, 2.37 MB

english, 2016

42

High-throughput drug profiling with voltage- and calcium-sensitive fluorescent probes in human iPSC-derived cardiomyocytes

Bedut, Stephane, Seminatore-Nole, Christine, Lamamy, Veronique, Caignard, Sarah, Boutin, Jean A., Nosjean, Olivier, Stephan, Jean-Philippe, Coge, Francis

Journal:

American Journal of Physiology - Heart and Circulatory Physiology

Year:

2016

Language:

english

File:

PDF, 2.91 MB

english, 2016

43

Assessments of cellular melatonin receptor signaling pathways: β-arrestin recruitment, receptor internalization, and impedance variations

Dupré, Clémence, Bruno, Olivier, Bonnaud, Anne, Giganti, Adeline, Nosjean, Olivier, Legros, Céline, Boutin, Jean A.

Journal:

European Journal of Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.91 MB

english, 2018

44

Gene expression profiling during hibernation in the European hamster

Gautier, Célia, Bothorel, Béatrice, Ciocca, Dominique, Valour, Damien, Gaudeau, Albane, Dupré, Clémence, Lizzo, Giulia, Brasseur, Chantal, Riest-Fery, Isabelle, Stephan, Jean-Philippe, Nosjean, Olivie

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 4.35 MB

english, 2018

45

Characterization of the various functional pathways elicited by synthetic agonists or antagonists at the melatonin MT 1 and MT 2 receptors

Legros, Céline, Dupré, Clémence, Brasseur, Chantal, Bonnaud, Anne, Bruno, Olivier, Valour, Damien, Shabajee, Preety, Giganti, Adeline, Nosjean, Olivier, Kenakin, Terrence P., Boutin, Jean A.

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 3.33 MB

2020

46

Molecular pharmacology of the mouse melatonin receptors MT1 and MT2

Séverine Devavry, Céline Legros, Chantal Brasseur, William Cohen, Sophie-Pénélope Guenin, Philippe Delagrange, Benoît Malpaux, Christine Ouvry, Francis Cogé, Olivier Nosjean, Jean A. Boutin

Journal:

European Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 730 KB

english, 2012

47

Comparative pharmacological studies of melatonin receptors: mt1, mt2 and mt3/qr2. tissue distribution of mt3/qr2

Olivier Nosjean, Jean-Paul Nicolas, Frederique Klupsch, Philippe Delagrange, Emmanuel Canet, Jean A Boutin

Journal:

Biochemical Pharmacology

Year:

2001

Language:

english

File:

PDF, 308 KB

english, 2001

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